Green Tea for Metabolic Health and Weight Management

Green tea and its bioactive compounds—such as EGCG and catechins—are widely recognized for their potential to enhance weight management and metabolic health.

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Research Interpretation

Green tea and its bioactive compounds—such as EGCG and catechins—are widely recognized for their potential to enhance weight management and metabolic health. A range of studies has explored high-dose green tea extract, Matcha green tea, and even combination supplements with ingredients like capsaicin and ginger to determine their effects on weight reduction, fat oxidation, and improvements in metabolic markers. These interventions have been tested across various populations, including obese women, adolescents, and women with conditions like PCOS, highlighting green tea's role as a natural aid in obesity and related metabolic dysfunction.

Protocols Studied in Research

High-Dose Green Tea Extract for Weight Reduction in Obese Women [1]

  • Protocol: In a randomized, double‑blind, placebo‑controlled trial, 102 centrally obese women (BMI ≥ 27 kg/m²; WC ≥ 80 cm) were assigned to receive high‑dose green tea extract (856.8 mg EGCG daily) or placebo for 12 weeks. Primary outcomes included weight, BMI, waist circumference, lipid profiles, and obesity-related hormones (ghrelin, adiponectin).
  • Outcome: The treatment group experienced significant weight loss (from 76.8 ± 11.3 kg to 75.7 ± 11.5 kg, p = 0.025), reductions in BMI and waist circumference, a consistent decrease in total cholesterol and LDL, lower ghrelin levels, and increased adiponectin – with excellent tolerability and no adverse events.

Matcha Green Tea Drinks for Enhanced Fat Oxidation During Exercise in Females [2]

  • Protocol: In a randomized, crossover study of 13 healthy females (mean age 27 ± 8 years), participants completed a 30‑minute brisk walking protocol (at 5–6 MET) under two conditions: after consuming Matcha green tea drinks (each made with 1 g Matcha, consumed the day before and 2 hours before exercise) versus a control beverage. Oxygen uptake, respiratory exchange ratio, and fat oxidation were measured.
  • Outcome: Matcha intake resulted in a lower respiratory exchange ratio (0.82 vs 0.84, p < 0.01) and enhanced fat oxidation (0.35 ± 0.11 vs 0.31 ± 0.10 g/min, p < 0.01) during the walk, indicating a metabolic advantage without affecting perceived exertion.

Coffee and Tea Consumption for Weight Control in Adolescents [3]

  • Protocol: In a randomized clinical trial among 48 obese adolescents (median age 13 years) receiving family-based nutritional counseling, participants were allocated to one of three arms: coffee (2 cups/day; 160 mg caffeine total), green tea (3 cups/day; 252 mg catechins and 96 mg caffeine total), or herbal tea (placebo, 3 cups/day). BMI and body fat percentage were assessed at 3 and 6 months.
  • Outcome: The coffee group showed a significantly greater reduction in BMI (–9.2% change) compared with the green tea (–2.3%) and placebo (0.76%) groups (p = 0.002), suggesting that, within a weight-loss program, coffee intake may offer additional benefits for adolescent weight control.

Green Tea Extract High for Reducing Body Fat and Cardiovascular Risk [4]

  • Protocol: In a 12‑week, double‑blind, parallel, multicenter trial, 240 Japanese subjects with visceral obesity were randomized to ingest either a green tea extract containing 583 mg catechins daily or a control supplement with 96 mg catechins. Outcomes included body weight, BMI, body fat mass, waist/hip circumference, visceral and subcutaneous fat areas, systolic blood pressure, and LDL cholesterol.
  • Outcome: The catechin group experienced significantly greater reductions in all anthropometric measures and visceral fat, as well as improvements in systolic blood pressure and LDL cholesterol, without adverse effects, suggesting that high-catechin green tea extract effectively reduces obesity and cardiovascular risk.

Green Tea Kombucha for Inflammation and Microbiota Modulation in Overweight Individuals [5]

  • Protocol: In a 10‑week randomized controlled trial, overweight participants were assigned to either a control group (caloric restriction only, n = 29) or a kombucha group (caloric restriction + 200 mL green tea kombucha daily, n = 30). Outcomes included weight, BMI, lipid accumulation product (LAP), plasma cytokines (IL-1β, IL-8, IL-6), and salivary microbiota diversity (via 16S rRNA sequencing).
  • Outcome: Both groups lost weight; however, the kombucha group showed a greater reduction in LAP (p = 0.029) and improved inflammatory profiles (lower IL-1β and IL-8, with IL-6 rising only in controls), alongside increased salivary microbiota diversity and a lower Bacillota/Bacteroidota ratio, indicating a beneficial modulation of inflammation and oral microbiota.

Green Tea for Weight Maintenance After Weight Loss [6]

  • Protocol: In a randomized, parallel, placebo‑controlled trial, 104 overweight/obese subjects (age 18–60; BMI 25–35 kg/m²) underwent a 4‑week very‑low‑energy diet to achieve a 5–10% weight loss, followed by a 13‑week weight-maintenance period during which participants received either green tea (containing 104 mg caffeine and 573 mg catechins per day, including 323 mg EGCG) or placebo.
  • Outcome: There was no significant difference in body weight regain between the green tea and placebo groups overall, though habitual high caffeine consumption was associated with higher weight regain in the green tea group, indicating that green tea may not enhance weight maintenance post‑loss.

Chinese Green Tea for Weight and Hormonal Profiles in Obese Women with PCOS [7]

  • Protocol: In a 3‑month, randomized, placebo‑controlled trial, 34 obese Chinese women with polycystic ovary syndrome were assigned to receive either green tea capsules or placebo. Outcomes measured included body weight, BMI, body fat content, and hormonal/biochemical profiles.
  • Outcome: The green tea group experienced a nonsignificant 2.4% weight reduction, while the control group had significant increases in weight, BMI, and body fat. Hormonal profiles remained unchanged, though a small but significant rise in triglycerides was observed. Fewer women in the green tea group remained amenorrheic, suggesting modest benefits on weight stabilization and menstrual regularity in PCOS.

Green Tea for Weight Reduction in Obese Thais [8]

  • Protocol: In this 12‑week randomized, controlled trial, 60 obese Thai subjects (BMI > 25 kg/m²) followed a standardized Thai diet (≈8373.6 kJ/day) and were randomized to receive either green tea or placebo. Body weight, BMI, body composition, resting energy expenditure, substrate oxidation, and biochemical markers (serum leptin, urine VMA) were assessed at baseline and during weeks 4, 8, and 12.
  • Outcome: The green tea group demonstrated significantly greater weight loss at weeks 8 and 12 (differences of 5.10 and 3.3 kg, respectively; p < 0.05), with increases in resting energy expenditure and enhanced fat oxidation (evidenced by lower respiratory quotient), supporting green tea’s role in promoting weight loss through metabolic enhancements.

Green Tea, Capsaicin, and Ginger Supplements for Weight Loss and Metabolic Improvement in Overweight Women [9]

  • Protocol: In a randomized, double‑blind, placebo‑controlled trial involving 50 overweight women, participants received dietary supplements containing a combination of green tea extract (125 mg), capsaicin (25 mg), and ginger extract (50 mg) twice daily with lunch and dinner for 8 weeks. Primary outcomes included changes in weight, BMI, and metabolic markers such as serum insulin, HOMA‑IR, QUICKI, and plasma glutathione (GSH) levels.
  • Outcome: Compared with placebo, the supplement group showed a significant weight reduction (–1.8 ± 1.5 kg vs. +0.4 ± 1.2 kg, p < 0.001) and BMI decrease (–0.7 ± 0.5 kg/m² vs. +0.1 ± 0.5 kg/m², p < 0.001), along with improved insulin sensitivity (lower insulin and HOMA‑IR, higher QUICKI) and increased plasma GSH levels, indicating beneficial effects on weight and metabolic profiles.

Research Interpretation: Summary and Conclusion

In simple terms, these studies suggest that high-dose green tea extract and high-catechin formulations can significantly reduce body weight, BMI, and waist circumference, while also improving lipid profiles and hormonal markers associated with obesity. Matcha green tea enhances fat oxidation during exercise, and combination supplements with green tea, capsaicin, and ginger further boost weight loss and improve insulin sensitivity. However, while green tea appears beneficial for initial weight reduction, its role in long-term weight maintenance may be limited.

Overall, these findings support green tea-based interventions as a promising, safe, and natural approach to improving metabolic health in various overweight and obese populations.

Publications

[1] Chen IJ, Liu CY, Chiu JP, Hsu CH. Therapeutic effect of high-dose green tea extract on weight reduction: A randomized, double-blind, placebo-controlled clinical trial. Clin Nutr. 2016 Jun;35(3):592-9. doi: 10.1016/j.clnu.2015.05.003. Epub 2015 May 29. PMID: 26093535.

[2] Willems MET, Şahin MA, Cook MD. Matcha Green Tea Drinks Enhance Fat Oxidation During Brisk Walking in Females. Int J Sport Nutr Exerc Metab. 2018 Sep 1;28(5):536-541. doi: 10.1123/ijsnem.2017-0237. Epub 2018 Jun 19. PMID: 29345213.

[3] Moran-Lev H, Cohen S, Zelber-Sagi S, Mazkeret Mayer E, Anafy A, Yerushalmy-Feler A, Lubetzky R. Effect of Coffee and Tea Consumption on Adolescent Weight Control: An Interventional Pilot Study. Child Obes. 2023 Mar;19(2):121-129. doi: 10.1089/chi.2022.0032. Epub 2022 May 30. PMID: 35639365; PMCID: PMC9986019.

[4] Nagao T, Hase T, Tokimitsu I. A green tea extract high in catechins reduces body fat and cardiovascular risks in humans. Obesity (Silver Spring). 2007 Jun;15(6):1473-83. doi: 10.1038/oby.2007.176. PMID: 17557985.

[5] Fraiz GM, Bonifácio DB, Lacerda UV, Cardoso RR, Corich V, Giacomini A, Martino HSD, Echeverría SE, Barros FAR, Milagro FI, Bressan J. Green Tea Kombucha Impacts Inflammation and Salivary Microbiota in Individuals with Excess Body Weight: A Randomized Controlled Trial. Nutrients. 2024 Sep 20;16(18):3186. doi: 10.3390/nu16183186. PMID: 39339787; PMCID: PMC11435194.

[6] Kovacs EM, Lejeune MP, Nijs I, Westerterp-Plantenga MS. Effects of green tea on weight maintenance after body-weight loss. Br J Nutr. 2004 Mar;91(3):431-7. doi: 10.1079/BJN20041061. PMID: 15005829.

[7] Chan CC, Koo MW, Ng EH, Tang OS, Yeung WS, Ho PC. Effects of Chinese green tea on weight, and hormonal and biochemical profiles in obese patients with polycystic ovary syndrome--a randomized placebo-controlled trial. J Soc Gynecol Investig. 2006 Jan;13(1):63-8. doi: 10.1016/j.jsgi.2005.10.006. PMID: 16378915.

[8] Auvichayapat P, Prapochanung M, Tunkamnerdthai O, Sripanidkulchai BO, Auvichayapat N, Thinkhamrop B, Kunhasura S, Wongpratoom S, Sinawat S, Hongprapas P. Effectiveness of green tea on weight reduction in obese Thais: A randomized, controlled trial. Physiol Behav. 2008 Feb 27;93(3):486-91. doi: 10.1016/j.physbeh.2007.10.009. Epub 2007 Oct 18. PMID: 18006026.

[9] Taghizadeh M, Farzin N, Taheri S, Mahlouji M, Akbari H, Karamali F, Asemi Z. The Effect of Dietary Supplements Containing Green Tea, Capsaicin and Ginger Extracts on Weight Loss and Metabolic Profiles in Overweight Women: A Randomized Double-Blind Placebo-Controlled Clinical Trial. Ann Nutr Metab. 2017;70(4):277-285. doi: 10.1159/000471889. Epub 2017 Jun 9. PMID: 28595182.